Drug efflux pumps in cancer resistance pathways [electronic resource] : from molecular recognition and characterization to possible inhibition strategies in chemotherapy / edited by Alejandro Sosnik, Reina Bendayan.
"Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strat...
| Uniform Title: | Cancer sensitizing agents for chemotherapy ;
v. 7. |
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| Other Authors: | |
| Language: | English |
| Published: |
London ; San Diego, CA :
Academic Press,
[2020]
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| Series: | Cancer sensitizing agents for chemotherapy ;
v. 7. |
| Subjects: | |
| Online Access: | |
| Variant Title: |
Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy |
| Format: | Electronic eBook |
| Summary: |
"Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers."-- Publisher's website |
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| Bibliography Note: | Includes bibliographical references and index. |
| ISBN: | 9780128141410 (online) |