Thermodynamics and kinetics of antisense oligonucleotide hybridization to a structured mRNA target / by S. Patrick Walton.
Antisense oligonucleotides have the potential to selectively inhibit the expression of any gene with a known sequence. Antisense-based therapies are under development for the treatment of infectious diseases as well as complex genetic disorders. Although there have been some remarkable successes, re...
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| Language: | English |
| Published: |
2002, ©2001.
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| Subjects: | |
| Local Note: |
MSU: Photocopy. |
| Dissertation Note: |
Thesis Sc. D. Massachusetts Institute of Technology, Department of Chemical Engineering 2002. |
| Physical Description: | 178 pages : illustrations ; 29 cm |
| Format: | Thesis Book |
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