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121227s1986 gw | o |||| 0|eng d |
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|z 9783540165019
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|z 9783642711541
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|a 9783642711527 (online)
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|a (EBZ)ebs1787706e
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|d EBZ
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|a msc
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|a QR46
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245 |
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|a Specificity and Function of Clonally Developing T Cells
|h [electronic resource]
|c edited by Bernhard Fleischer, Jörg Reimann, Hermann Wagner.
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250 |
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|a 1st ed. 1986.
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264 |
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|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg :
|b Imprint: Springer,
|c 1986.
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490 |
1 |
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|a Current Topics in Microbiology and Immunology,
|x 2196-9965 ;
|v 126
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505 |
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|a A: Development of T Lymphocytes in the Thymus -- Introductory Remarks -- Development of T Lymphocytes Within the Thymus and Within Thymic Nurse Cells. With 3 Figures -- Thymus Development -- Major Histocompatibility-Restricted Cytolytic T-Lymphocyte Precursors from the Thymus of In Vivo Primed Mice: Increased Frequency and Resistance to Anti-Lyt-2 Antibody Inhibition. With 1 Figure -- Thymic Stem Cells: Their Interaction with the Thymic Stroma and Tolerance Induction -- B: Murine T-Cell Receptor Genes -- Organization, Rearrangement, and Diversification of Mouse T-Cell Receptor Genes. With 1 Figure -- Expression of T-Cell Receptor by a Mouse Monoclonal Antigen-Specific Suppressor T-Cell Line -- Somatic Variation of Antigen-Recognition Specificity in H-2b-TNP-Specific Cytotoxic T-Cell Clones -- The Change of Specificity, Karyotype, and Antigen-Receptor Gene Expression is Correlated in Cytotoxic T-Cell Lines -- C: Phenotype and Functional Potential of T-Cell Clones -- Introductory Remarks -- A Study of the Functional Potential of Mouse T-Cell Clones -- Generation, Propagation, and Variation in Cloned, Antigen-Specific, Ia-Restricted Cytolytic T-Cell Lines -- Significance of T4 or T8 Phenotype of Human Cytotoxic T-Lymphocyte Clones. With 1 Figure -- Natural and Unnatural Killing by Cytolytic T Lymphocytes. With 2 Figures -- Acquisition of Suppressive and Natural Killer-Like Activities Associated with Loss of Alloreactivity in Human “Helper” T-Lymphocyte Clones. With 3 Figures -- Expression and Function of Class II I-Ak Antigens on an Antigen-Specific T-Suppressor Cell Clone. With 2 Figures -- D: Signal Requirements for T-Cell Activation -- Introductory Remarks -- Heterogeneity of the Signal Requirements During the Primary Activation of Resting Lyt-2+ Cytotoxic T-Lymphocyte (CTL) Precursors into Clonally Developing CTL. With 2 Figures -- Regulation of Lytic Function by Recombinant IL2 and Antigen. With 4 Figures -- The Target Structure for T11: A Cell Interaction Molecule Involved in T-Cell Activation? With 3 Figures -- Antigen- and Lectin- Sensitized Murine Cytolytic T Lymphocyte- Precursors Require Both Interleukin 2 and Endogenously Produced Immune (?) Interferon for Their Growth and Differentiation. With 3 Figures -- Activation Requirements for Resting T Lymphocytes -- E: Self-Nonself Discrimination in the T-Cell Compartment -- Introductory Remarks -- Functional Clonal Deletion and Suppression as Complementary Mechanisms in T Lymphocyte Tolerance -- Human T Cell Clones, Tolerance, and the Analysis of Autoimmunity. With 1 Figure -- Antiself Suppressive (Veto) Activity of Responder Cells in Mixed Lymphocyte Cultures. With 6 Figures -- Analysis of T Suppressor Cell Mediated Tumor Escape Mechanisms. With 2 Figures -- The T-Cell Receptor Recognizes Nominal and Self Antigen Independently. A Theoretical Alternative to the Modified Self Concept. With 3 Figures -- F: T-Cell-Mediated Autoreactivity -- Introductory Remarks -- T-Cell Reactivity to Polymorphic MHC Determinants. I. MHC-Guided T-Cell Reactivity -- T-Cell Reactivity to Polymorphic MHC Determinants. II. Self-Reactive and Self-Restricted T Cells. With 6 Figures -- T-Cell Reactivity to Polymorphic MHC Determinants. III. Alloreactive and Allorestricted T Cells. With 9 Figures -- Appearance of New Specificities in Lectin-Induced T-Cell Clones Obtained from Limiting Dilution T-Cell Cultures. With 2 Figures -- Syngeneic Cytotoxicity and Veto Activity in Thymic Lymphoid Colonies and Their Expanded Progeny. With 4 Figures -- Functional Analysis of a Self-I-A Reactive T-Cell Clone Which Preferentially Stimulates Activated B Cells -- Indexed in Current Contents.
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650 |
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|a Medical microbiology.
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650 |
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|a Allergy.
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650 |
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|a Immunology.
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700 |
1 |
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|a Fleischer, Bernhard.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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700 |
1 |
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|a Reimann, Jörg.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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700 |
1 |
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|a Wagner, Hermann.
|e editor.
|4 edt
|4 http://id.loc.gov/vocabulary/relators/edt
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer Book Archive - Biomedicine & Life Sciences
|d Springer Nature
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776 |
0 |
8 |
|i Printed edition:
|z 9783642711541
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776 |
0 |
8 |
|i Printed edition:
|z 9783540165019
|
776 |
0 |
8 |
|i Printed edition:
|z 9783642711534
|
776 |
1 |
|
|t Specificity and Function of Clonally Developing T Cells
|
830 |
|
0 |
|a Current Topics in Microbiology and Immunology,
|x 2196-9965 ;
|v 126
|
856 |
4 |
0 |
|y Access Content Online(from Springer Book Archive - Biomedicine & Life Sciences)
|u https://ezproxy.msu.edu/login?url=https://link.springer.com/10.1007/978-3-642-71152-7
|z Springer Book Archive - Biomedicine & Life Sciences: 1986
|