Organic synthesis [electronic resource] : the disconnection approach / Stuart Warren and Paul Wyatt.

Bibliographic Details
Main Author: Warren, Stuart G.
Other Authors: Wyatt, Paul
Language:English
Published: Chichester, UK : John Wiley & Sons Ltd., 2008.
Edition:2nd ed.
Subjects:
Online Access:
Variant Title:
Organic Synthesis: The Disconnection Approach
Format: Electronic eBook
Contents:
  • The disconnection approach
  • Basic principles : synthons and reagents synthesis of aromatic compounds
  • Strategy I : the order of events
  • One-group C-X disconnections
  • Strategy II : chemoselectivity
  • Two-group C-X disconnections
  • Strategy III : reversal of polarity, cyclisations, summary of strategy
  • Amine synthesis
  • Strategy IV : protecting groups
  • One group C-C disconnections I : alcohols
  • General strategy A : choosing a disconnection
  • Strategy V : stereoselectivity A
  • One group C-C disconnections II : carbonyl compounds
  • Strategy VI : regioselectivity
  • Alkene synthesis
  • Strategy VII : use of acetylenes (alkines)
  • Two-group C-C disconnections I : Diels-Alder reactions
  • Strategy VIII : introduction to carbonyl condensations
  • Two-group C-C disconnections II : 1,3-difunctionalised compounds
  • Strategy IX : control in carbonyl condensations
  • Two-group C-C disconnections : 1,5-difunctionalised compounds
  • Strategy X : aliphatic nitro compounds in synthesis
  • Two-group disconnections IV : 1,2-difunctionalised compounds
  • Strategy XI : radical reactions in synthesis
  • Two-group disconnection V : 1,4-difunctionalised compounds
  • Strategy XII : reconnection
  • Two-group C-C disconnections VI : 1,6-diCarbonyl compounds
  • General strategy B : strategy of carbonyl disconnections
  • Strategy XIII : introduction to ring synthesis : saturated heterocycles
  • Three-membered rings
  • Strategy XIV : rearrangements in synthesis
  • Four-membered rings : photochemistry in synthesis
  • Strategy XV : the use of ketenes in synthesis
  • Five-membered rings
  • Strategy XVI : pericyclic reactions in synthesis : special methods for five-membered rings
  • Six-membered rings
  • General strategy C : strategy of ring synthesis
  • Strategy XVII : stereoselectivity B
  • Aromatic heterocycles
  • General strategy D : advanced strategy.